Probiotics-Prebiotics Research

Probiotics are microorganisms that are believed to produce health advantages once consumed. A major growth of the potential marketplace for probiotics has led to higher needs for scientific substantiation of supposed benefits conferred by the microorganisms. Bacterial cell surface macromolecules are key factors in this beneficial microorganism–host crosstalk, as they can interact with host pattern recognition receptors (PRRs) of the gastrointestinal mucosa.
 
The human GI tract is colonised by a colossal and complex association of mainly bacterial cells. This microbiota consists of a minimum of 1013 microbes, dominated by anaerobic bacteria, comprising over 1,000 species, of which the majority cannot be cultured under laboratory conditions. Research on host–probiotic interactions can benefit from well-documented host–microorganism studies that span the spectrum from pathogenicity to mutualism.
 

  • Probiotics in Health and Diseases
  • Role of probiotics, prebiotics and synbiotics for gut heath benefits
  • Molecular analysis
  • Role of Probiotics in modulation of host immune response
  • Commensal Microbes
  • Use of probiotic bacteria as antigen delivery vehicle
  • Monitoring microbial Responses

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